Ava L.

My name is Ava, and I am a rising sophomore at Mercer Island High School. Participating in the Fred Hutch Pathways Research Explorers Program has been an incredible introduction to biomedical research and the world of wet-lab science. Throughout the program, I had the opportunity to explore the groundbreaking research being conducted at Fred Hutch through lab tours, presentations, and conversations with accomplished scientists. I also developed essential laboratory skills, including micropipetting, gel electrophoresis, and PCR.

Me micropipetting

One of the most meaningful parts of the program was learning about the careers of the scientists who spoke to us. My personal highlight was Dr. Stoddard’s presentation and lab tour. His passion for his work was immediately evident, and his enthusiasm made his research fascinating and memorable. He shared stories from throughout his career, from attempting to crystallize proteins during his PhD at MIT to sending experiments on Soviet rockets into space. He eventually discovered that the absence of gravity did not affect protein crystallization as he had expected. His story demonstrated how scientific discoveries often come from unexpected results and experiences. The lab tour was equally memorable. We had the opportunity to see an X-ray crystallography machine in his lab, a piece of equipment that had been used to solve the structures of many proteins. Learning how the machine works gave me a new appreciation for the technology behind research. Dr. Stoddard’s presentation and tour emphasized the importance of trial and error in science. In his lab, one method of determining protein structures involves attempting to crystallize proteins in many different solutions. Some proteins crystallize easily, while others may not crystallize at all. There is not always a clear way to predict which outcome will occur. This showed me that failure is not necessarily a setback in research.

X-Ray Crystallography Machine in Dr. Stoddard’s Lab

Another highlight of the program was the presentation by Dr. Raabya and Dr. Paul. They shared their personal career journeys and explained how their paths changed significantly along the way. Their stories were especially meaningful because they showed that there is no single path to a successful career in science. We still have many years ahead of us to explore our interests, discover new opportunities, and determine what we want our futures to look like. Dr. Raabya also introduced us to the Japanese concept of ikigai: a reason for being. It involves considering what you love, what you are good at, what the world needs, and what you can be paid for. I found this concept particularly meaningful because it. I found this concept particularly meaningful because it encouraged me to think beyond simply choosing a career and instead consider what kind of impact and purpose I want to have. Ikigai is a concept I hope to carry with me as I continue exploring interests and deciding where my journey may take me.

Finally, one of the most important things I will carry with me from this program is the value of connection. Scientists share ideas, learn from one another, and work together to solve problems that would be difficult to approach alone. I experienced this sense of collaboration within our own group. During the first few days, many of us were unfamiliar with one another. However, as we participated in activities and shared experiences, we gradually became much closer and created memories and friendships that I will remember long after the program ends.

                                                            2026 Explorers Session 2

Through the various Mafia games, pranks, and memories made, the Pathways Research Explorers Program has been a fantastic experience that has taught me valuable lessons, both in and out of the lab, which I will carry with me throughout my journey and future career.